The 3-pronged approach to defeating the coronavirus

Testing, treatments, and vaccines are required to tackle coronavirus—but it's complicated.

The 3-pronged approach to defeating the coronavirus

Good afternoon, readers.

We learned this morning that about 26 million Americans have lost their jobs amid the coronavirus crisis. Real unemployment now stands at more than 20%. The U.S. has crossed 850,000 confirmed cases (those we know of so far) and is creeping up on 50,000 confirmed deaths—the most in the world.

As we explored at length in this story, the reasons for this failure are widespread and complicated. There will have to be an ultimate accounting for that. In the meantime, however, the priority is digging the nation out of this catastrophic public health and economic hole. So, how do we do that?

I explored the multi-pronged approach we’ll have to take in order to tackle this insidious and sometimes inscrutable pathogen in the latest print issue of Fortune.

In conversations with dozens of experts across the medical industry, here’s what became clear: We need to test; we need to treat; and we need to create vaccines for long-term protection.

That may seem obvious after months of quarantine, but the logistics are a lot more complicated. And that’s where the biopharma industry truly has a chance to shine and show whether or not it can lead in the midst of the chaos.

In short, adequate—and accurate—testing can help slowly re-open the economy and mitigate risk; the development of effective treatments can lower the burden on the health care system and hospitals; and a longer-term vaccine, should one emerge (and that’s an open question), can provide global peace of mind.

All of that is a heavy lift. The (very qualitative) good news is: At least a number of firms seem to be stepping up. “There’s an incredible sense of urgency,” George Scangos, the former chief of Biogen and current CEO of Vir Biotechnology, a company working on both ­COVID-19 treatments and vaccines, tells me. “The number of companies that want to contribute regardless of whether you make a lot of money is incredible.”

We’ll see if those aspirations can ultimately salvage what this scourge has wrought.

Read on for the day’s news, and see you next week.

Sy Mukherjee

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Nursing homes plead for more coronavirus testing as ‘bodies keep piling up’

“We feel like we’ve been ignored,” said the CEO of the American Health Care Association, which represents long-term care facilities

Nursing homes plead for more coronavirus testing as ‘bodies keep piling up’

After two months and more than 10,000 deaths that have made the nation’s nursing homes some of the most terrifying places to be during the coronavirus crisis, most of them still don’t have access to enough tests to help control outbreaks among their frail, elderly residents.

Neither the federal government nor the leader in nursing home deaths, New York, has mandated testing for all residents and staff. An industry group says only about a third of the nation’s 15,000 nursing homes have ready access to tests that can help isolate the sick and stop the spread. And homes that do manage to get a hold of tests often rely on luck and contacts.

“It just shows that the longer that states lapse in universal testing of all residents and staff, we’re going to see these kinds of stories for a very long time,” said Brian Lee of the advocacy group Families for Better Care. “Once it’s in, there’s no stopping it and by the time you’re aware with testing, too many people have it. And bodies keep piling up.”

That became clear in some of the nation’s biggest nursing home outbreaks. After a home in New York City’s Brooklyn borough reported 55 coronavirus deaths last week, its CEO acknowledged it was based entirely on symptoms and educated guesses the dead had COVID-19 because they were unable to actually test any of the residents or staff.

At a nursing home in suburban Richmond, Va., that has so far seen 49 deaths, the medical director said testing of all residents was delayed nearly two weeks because of a shortage of testing supplies and bureaucratic requirements. By the time they did, the spread was out of control, with 92 residents positive.

Mark Parkinson, CEO of the American Health Care Association, which represents long-term care facilities, says “only a very small percentage” of residents and staff have been tested because the federal and state governments have not made nursing homes the top priority.

“We feel like we’ve been ignored,” Parkinson said. “Certainly now that the emphasis has gone away from hospitals to where the real battle is taking place in nursing homes, we should be at a priority level one.”

Two-thirds of U.S. nursing homes still don’t have “easy access to test kits” and are struggling to obtain sufficient resources, said Chris Laxton, executive director of The Society for Post-Acute and Long-Term Care Medicine.

“Those nursing home leaders who have developed good relationships with their local hospitals and health departments seem to have better luck,” said Laxton, whose organization represents more than 50,000 long-term care professionals. “Those that are not at the table must fend for themselves.”

Public health officials have long argued that current measures like temperature checks aren’t sufficient. They can’t stop workers with the virus who aren’t showing signs from walking in the front door, and they don’t catch such asymptomatic carriers among residents either. What is needed is rigorous and frequent testing—”sentinel surveillance,” White House virus chief Deborah Birx calls it—to find these hidden carriers, isolate them, and stop the spread.

The U.S. is currently testing roughly 150,000 people daily, for a total of 4.5 million results reported, according to data compiled by the COVID Tracking Project. Public health experts say that needs to be much higher. “We need likely millions of tests a day,” said Dr. Ashish Jha, director of the Harvard Global Health Institute.

The federal Health & Human Services Department told The Associated Press that ”there are plenty of tests and capability for all” priority categories and that all should be tested. The agency also noted one of President Donald Trump’s briefings this week in which he underscored the states’ role in coordinating testing.

Only one governor, West Virginia’s Jim Justice, appears to be mandating testing for all nursing homes without conditions. Detroit Mayor Mike Duggan ordered tests at all 26 nursing in the city, using new kits that can spew out results in 15 minutes. Massachusetts abruptly halted a program to send test kits directly to nursing homes this week after 4,000 of them turned out to be faulty. New Hampshire teamed with an urgent-care company to test care workers. Several states including Colorado, Florida, Maryland, Tennessee, and Wisconsin have dispatched National Guard testing strike teams.

“It’s a snapshot,” New Hampshire Health Care Association President Brendan Williams said of the national piecemeal approach. “We need a motion picture.”

While the federal government promised this week to start tracking and publicly releasing nursing home infections and deaths, which could help identify hotspots, that work was only beginning. In the meantime, The AP’s own tally from state health departments and media reports put the count at 10,217 deaths from outbreaks in nursing homes and long-term care facilities nationwide. About a third of those are in New York.

New York Gov. Andrew Cuomo, who has described COVID-19 in nursing homes as “fire through dry grass,” said he would ideally like to see any resident, staffer or visitor seeking to enter a nursing home take a rapid test that would come back in 20 minutes. But, he said, “that’s millions of tests.”

Dr. Roy Goldberg, medical director of a nursing home in New York City’s Bronx borough that this past week reported 45 deaths, said his facility still can’t test asymptomatic patients because of shortages that have limited testing to those showing fever or a cough.

“This isn’t what anyone signed up for,” Goldberg said. “It just breaks my heart that the long-term care industry is going to end up being totally scapegoated on this.”

Amid the tragedies have emerged hopeful cases in which early and aggressive testing has made huge difference.

After the first of two deaths at a Sheboygan, Wis., nursing home and other residents and staffers started falling ill, administrator Colinda Nappa got on the phone and pleaded with state officials: “I got to know what is going on.”

A 65-member National Guard testing unit soon showed up, donned head-to-toe protective suits, and quickly tested nearly 100 residents and 150 staffers.

In all, 19 residents and staffers tested positive and all are either now housed in a special section of the building or quarantined at home. There have been no more deaths.

In the Seattle area, which had the nation’s first major nursing home outbreak that eventually claimed 43 lives, health officials are targeting their testing efforts on homes that have shown little sign of the disease.

Their plans for testing at 19 such facilities are aimed at trying to head off hotspots by quickly identifying and containing cases. In conjunction with ramped-up capacity for tracing contacts of patients, it’s considered an important prerequisite to reopening he economy.

This past week, medical professionals led by the University of Washington’s Dr. Thuan Ong went room by room through a nursing home in a highly orchestrated ballet of swabbing and bagging. In all, 115 residents were tested and results came back the next day as all negative—a development that drew cheers from the facility’s staff.

“One of the greatest values,” Ong said, “is to catch it before it spreads.”

More coronavirus coverage from Fortune:

—Bill Gates explains how to beat the coronavirus pandemic
—Elective surgeries—mostly paused due to the pandemic—are —World Health Organization says —Late payments soar, revealing —14% of women considered quitting their jobs because of the coronavirus pandemic
—Forget “wet markets” and bats: For scientists, f—Out of work, but not unemployed: —PODCAST: COVID-19 might have upended the concept of the —VIDEO: 401(k) withdrawal penalties waived for anyone hurt by COVID-19

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